| Over the long-term, acid reflux (even when it doesn't cause discomfort) may lead to a condition known as Barrett's esophagus, in which the normal lining cells of the esophagus are replaced by cells more reminiscent of those lining the stomach and/or intestine. This is the body's response to long-term acid exposure as these other cell types are more resistant to the effects of such exposure. The problem is that over the long term, the alterations associated with Barrett's lead a much higher incidence of glandular cancer of the esophagus, a serious and often fatal disease. Therefore Aciphex, or other strong medications that inhibit acid production, are used to avoid this serious consequence down the road, regardless of symptoms. |