The below information on Actiq has been taken from official FDA sources, but we cannot guarantee it's accuracy. Please use this site for educational purposes only. This site does not replace a proper discussion with your doctor.

    Brand Name:Actiq
    Generic:Fentanyl Citrate
This drug was approved by the FDA in one form or another on:
1998-11-04 ,
This drug is made in one form or another by the following companies:
Cephalon, Inc.
This drug is available in the following forms:
Troche, Lozenges and Oral transmucosal
View the actual FDA approved label for this drug at the following links:

About Actiq

Actiq is a prescription medicine that contains the medicine fentanyl. Actiq is a federally controlled substance (CII) because it is a strong opioid pain medicine that can be abused by people who abuse prescription medicines or street drugs.

Precautions for Actiq

  • Do not drive, operate heavy machinery, or do other dangerous activities until you know how Actiq affects how alert you are. Actiq can make you sleepy. Ask your doctor when it is okay to do these activities.
  • Do not drink alcohol while using Actiq. It can increase your chance of getting dangerous side effects.
  • Do not take any medicine while using Actiq until you have talked to your doctor. Your doctor will tell you if it is safe to take other medicines while you are using Actiq. Be especially careful about medicines that make you sleepy such as other pain medicines, anti-depressant medicines, sleeping pills, anxiety medicines, antihistamines, or tranquilizers.

Side Effects of Actiq

  • Actiq can cause serious breathing problems that can become life-threatening, especially if used the wrong way. See “What is the most important information I should know about Actiq?”
  • Call your doctor or get emergency medical help right away if you:
    • have trouble breathing
    • have extreme drowsiness with slowed breathing
    • have slow shallow breathing (little chest movement with breathing)
    • feel faint, very dizzy, confused, or have unusual symptoms

    These can be symptoms that you have taken too much (overdose) Actiq or the dose is too high for you. These symptoms may lead to serious problems or death if not treated right away.

  • Actiq can cause your blood pressure to drop. This can make you feel dizzy if you get up too fast from sitting or lying down.
  • Actiq can cause physical dependence. Do not stop taking Actiq or any other opioid without talking to your doctor. You could become sick with uncomfortable withdrawal symptoms because your body has become used to these medicines. Physical dependency is not the same as drug addiction.
  • There is a chance of abuse or addiction with Actiq. The chance is higher if you are or have been addicted to or abused other medications, street drugs, or alcohol, or if you have a history of mental problems. The most common side effects of Actiq are nausea, vomiting, dizziness and sleepiness. Other side effects include headache, low energy and constipation. Constipation (not often enough or hard bowel movements) is a very common side effect of pain medicines (opioids) including Actiq and is unlikely to go away without treatment. Talk to your doctor about dietary changes, and the use of laxatives(medicines to treat constipation) and stool softeners to prevent or treat constipation while taking Actiq. Actiq contains sugar. Cavities and tooth decay have occurred in patients taking Actiq. When taking Actiq, you should talk to your dentist about proper care of your teeth. Talk to your doctor about any side effects that bother you or that do not go away. These are not all the possible side effects of Actiq. For a complete list, ask your doctor.

Who Should Not Take Actiq

Do Not Take Actiq if you:

  • are not already taking other opioid pain medicines for your constant (around-the-clock) cancer pain. Never use Actiq for short-term pain from injuries or surgery or pain that will go away in a few days, such as pain from doctor or dentist visits, or any short-lasting pain.
  • are allergic to anything in Actiq. The active ingredient in Actiq is fentanyl. See the end of this Medication Guide for a complete list of ingredients in Actiq.

Interactions with Actiq

Some MEDICINES MAY INTERACT with Actiq Lozenge. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Naltrexone because the effectiveness of Actiq Lozenge may be decreased
  • Alcohol, amiodarone, azole antifungals (eg, fluconazole), barbiturate anesthetics (eg, thiopental), benzodiazepines (eg, alprazolam), cimetidine, HIV protease inhibitors (eg, ritonavir), macrolides (eg, erythromycin), MAO inhibitors (eg, phenelzine), or sodium oxybate (GHB) because side effects such as difficulty breathing, seizures, and disorientation may occur
  • Barbiturate anesthetics (eg, thiopental), benzodiazepines (eg, alprazolam), sibutramine, orsodium oxybate (GHB) because actions and side effects of these medicines may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Actiq Lozenge may interact with other medicines that you take.

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