Aggrastat

The below information on Aggrastat has been taken from official FDA sources, but we cannot guarantee it's accuracy. Please use this site for educational purposes only. This site does not replace a proper discussion with your doctor.


    Brand Name:Aggrastat
    Generic:Tirofiban Hydrochloride
    Availability:Prescription
This drug was approved by the FDA in one form or another on:
1998-05-14 ,
This drug is made in one form or another by the following companies:
Merck & Co., Inc.
This drug is available in the following forms:
Injectables
View the actual FDA approved label for this drug at the following links:
http://www.fda.gov/cder/foi/nda/99/20912S001_AGGRASTAT_prntlbl.pdf

About Aggrastat

Aggrastat is used for patients having chest pain that lasts longer than typical angina and that is not controlled by the medicines that are usually effective for angina. Aggrastat prevents blood clots from forming, thereby reducing the number of patients having heart attacks or needing heart surgery.

Precautions for Aggrastat

Aggrastat should be used with caution if you have a decreased blood platelet count or disease of the retina of the eye associated with bleeding.

Side Effects of Aggrastat

The most common complication reported during testing of the product was excessive bleeding. The increased bleeding is why some people (those who have had recent surgery, and other examples mentioned above) should not be given Aggrastat.

Other possible side effects occurring in at least 3% or more of the people studied:

  • Pelvic pain
  • Slow heart rate
  • Tear in the coronary artery
  • Leg pain
  • Dizziness

Who Should Not Take Aggrastat

You should not be given Aggrastat if you ever had the following conditions:

  • Bleeding in the brain, brain tumor or ballooning of a blood vessel in the brain
  • History of reduced number of platelets in the blood from prior treatment with Aggrastat

You should not be given Aggrastat if within the past 30 days you have had:

  • Medical diagnosis of internal bleeding or of unusual tendency toward bleeding
  • Medical diagnosis of stroke
  • Major surgery or trauma

You should also not be given Aggrastat if now:

  • Your doctor sees signs of ongoing injury to the aorta (the large blood vessel that carries blood from the heart) or signs of pericarditis (inflammation of the sac surrounding the heart)
  • You have very high blood pressure (greater than 180/110)
  • You are being treated with eptifibatide (Integrilin)
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Recent Forum Posts on Aggrastat

No Subject

Yes I would like to give my feed back. I think this product should be no longer available. This needs to be taken of the market now! It had major devistating affects on my grandfather, he bled to death on the operating table from aggrastat. The doctor could not believe the amount of blood loss and trauma his body was suffering as he was bleeding to death. The Dr. said that she had never seen anything like this in her carrer and was devistated. Watching your family member bleed to death in front of your very eyes isn't something you can erase. I can't even tell you the emotional affects it had on my family. I myself suffered from flash backs,and major depression.I was put on medication to help with the flash backs and depression. It has been 2 and a half years and I am just starting to beable to cope and go on with my daily life. I pray and hope nobody has had to experience something like this.


measurement

4/2/04

I have been asked by Professor Alan Keenan professor of Pharmacology in University College Dublin to get some information on measuring the concentration of Aggrastat in solution
Would it be possible for someone to contact him directly .
His email address is Alan.Keenan@ucd.ie

I would appreciate an acknowledgement of your receipt of this email and your intention to help this authority on drugs.

Thank you

Michael Higgins

Director

Lennox Laboratory Supplies
Dublin


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