The below information on Amerge has been taken from official FDA sources, but we cannot guarantee it's accuracy. Please use this site for educational purposes only. This site does not replace a proper discussion with your doctor.

    Brand Name:Amerge
    Generic:Naratriptan Hydrochloride
This drug was approved by the FDA in one form or another on:
1998-02-10 ,
This drug is made in one form or another by the following companies:
This drug is available in the following forms:
View the actual FDA approved label for this drug at the following links:

About Amerge

Amerge is used for the short term treatment of most types of migraine attacks in adults. Amerge is not used to prevent migraines, or to decrease the number of migraine attacks. Amerge has not been shown to treat cluster headaches.

Side Effects of Amerge

Some signs of rare but serious side effects include:

  • Possible life-threatening serotonin syndrome when used with SSRI or SNRI medicines.
  • Pain, pressure or tightness in the chest or throat. If severe, or does not go away, call your healthcare professional right away. If this happens at all, discuss with your healthcare professional before taking any more Amerge.
  • Rarely, people have a serious allergic reaction to Amerge. This could cause shortness of breath, wheeziness, heart throbbing, swelling of eyelids, face, or lips, or a skin rash, lumps or hives. If this happens, tell your healthcare professional right away.

Other side effects may include:

  • Nausea
  • Sleepiness
  • Tingling or burning feeling
  • Headache
  • Dry mouth

Who Should Not Take Amerge

You should not take Amerge if you have (or have had) any of following conditions:

  • uncontrolled high blood pressure
  • heart disease or a history of heart disease
  • hemiplegic or basilar migraine (if you are not sure about this, ask your healthcare professional)
  • stroke
  • circulation (blood flow) problems to your arms, legs, and bowels
  • have taken another migraine medicine in the same drug class as Amerge or other migraine medicines that contain ergotamine, dihydroergotamine, or methylsergide in the last 24 hours (ask your healthcare professional for a list of these medicines if you are unsure)
  • severe liver disease

Interactions with Amerge

Amerge and certain other medicines can interact with each other. Tell your healthcare professional about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Some medicines may affect how Amerge works or Amerge may affect how your other medicines work. Know the medicines you take. Keep a list of them with you to show your healthcare professional.

Especially tell your healthcare professional if you:

  • take a SSRI or SNRI medicine
  • have taken another migraine medicine in the same drug class as Amerge or other migraine medicines that contain ergotamine, dihydroergotamine, or methylsergide in the last 24 hours
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Recent Forum Posts on Amerge

Amerge is marvelous, but. . .

Ever since I started using Amerge, 9 years ago, I've had a way out of the excruciating pain of migraine. Recently, I started treatment for lymphoma with an monioclonal antibody (Rituxan, or Rituximab). This has caused daily headaches. Amerge stops them - however, I am afraid of taking Amerge on a daily or near-daily basis because of potential harm to the kidneys. Does anyone know about this? Is anyone out there who is using Amerge while in some form of chemo treatment? Thanks, Anticat

amerge, a little miracle pill

I have had migranes since i was a little kid. It started with an aura and then developed a whole of symptoms including distorted vision, numbness on any body part, vomiting until exhaustion and then the splitting migrane headed that would not get relief with any over the counter medication. Through the years some of the symptoms when i get the migrane have subsided, but i still get the headache with nausea and the is no medication that would relief it unless is Amerge. I have taken Imitrex and it makes me feel worse. Amerge is the only thing that works for me. Even when I have taken it when the headache is most intense in about 2 to three hours the headache is completely gone!! I call it a little miracle. Thank God and whoever made this medicatio. I can only wish it was not so expensive, I can only buy one or two at a time. At any rate, I am thankfull it is here and it really works!!!!!

amerge 2.5

I had suffered from migrane headeaches since i was in sixth grade. Every time i had an attack it was different than the one before. When I first got married it subsided somewhat and symptoms changed. I could never take anything for it as i either throw it up or it did not help me at all. One day talking to my ginecologyst about the migrane he prescribed amerge and the first time i took it i got rid of the migrane withing 20 minutes of having take it. For me, there are little miracles in life and amerge is one of them. Nevertheless, my sister suffers from the same migranes and not wanting to see her suffer i gave her one to see if it would help her, but to my surprise it didn't. Well life can't be perfect. I just wish it was not so expensive.


I am on a MAOI drug 'nardil'. My doctor gave me Amerge to take but I am terribly worried that this drug will interact with the Nardil that I am on. Any comments?


Doctor gave me 3 samples, after experiencing the neck pain I found with Imitrex or Zomig, I only took 1/2 with my migraine. I found no neck pain or stiff neck after 1/2 hour so I took the rest of it. The headache was gone and then returned later on. I am trying to find complete relief after more than 6 months of daily migraine. At the price of the medication after my insurance kicked in, I get 9 pills for $48. I am wondering how long before the daily migraines will stop? Are there other meds to help? I am taking 1 per day for 5 days now and headache still coming each day, although today, Sunday, August 10, did not wake with headache and didn't come until around 1:00 pm. It does take away the headache but I am not sure it is a permanent solution for me.

It works!

If you can afford it or if your prescription drug plan covers it, use Amerge for your migraines. I've had classic migraines with aura since age 13 (now age 40), and in the past I had to go to the ER for big narcotics to get relief. Amerge has stopped all that. It works.

No Subject

I am 36 year old and i have been having classic migraines for past one year and my doctor prescribed Amerge. I have had migraine twice since and i took Amerge, My headache goes away but i have ringing in the ears.... especially in the night when i lay down. This is new and started about the same time when i started taking Amerge. I have decided not to take Amerge when i get a migraine next time and see if it stops ringing in my ears.

Amerge rare side effect

I took Amerge for the first time for a severe migraine and within 5 hours suffered the rare side effect of horrible abdominal pains! I called my doctor and said they had never seen such a severe reaction, they told me to take a pain reliver, but not advil or mortrin. Seven hours later, I still have them but not as severe.

I'll take the migraine over these abdominal pains, so no more Amerge for me.

Amerge works for me!

I have been taking Amerge for a couple of years. I'm 37 and have been having migraines since I was a teenager. I have tried multiple migraine medications that did not work but the Amerge works for me without any side effects. I am limited to 8 pills per month and my share of the cost is $33.00 which is well worth it. My only problem is that every month when it is time to refill the medication, it is such a hassle between the pharmacy, my dr's office and the insurance company to get this medication refilled. My doctor is wonderful and has no problems processing the paperwork but he is tired of dealing with this every month just as much as I am. Another problem I have is that I usually need more than 8 pills a month. I get 1-2 migraines a month that come out of the blue. I always get menstrual migaines every month that start 1-2 days before the actual period and last through a 7 day cycle, sometimes needing to take 2 in a 24 hour period (I take the 2.5 mg strength Amerge). My doctor gives me samples when he has them available. If I don't have access to Amerge, it doesn't matter what else I take, I end up in the ER for a shot. Occasionally, even with Amerge I end up in the ER for a shot but that is usually because I took the medication too late (with only 8 a month, I have to try to stretch it out). Thankfully, I haven't had to go to the hospital in 8 months! Amerge really works for me when I can take it right when I'm getting a migraine. Even if it has long term side effects, I'd rather live a quality life now than a longer life with more pain.

No Subject

I used to lose a day of my life due to migraine-unable to function-I tried Imitrex-that just put me to sleep & when I awoke the migraine was still there. I was given Maxalt-that did nothing. Then a neurologist gave me Amerge. If I take it right away, in about an hour the migraine is completely gone and I can go on with my day. Sometimes I wait to see if I can do without it(I don't like to take drugs) but the Amerge still works in about an hour's time. The only ill effect is feeling more tired later on-but I can go to work and function and not feel like I just want someone to shoot me and put me out of misery! I have been taking it for years and my only concern, the reason I'm checking out this website, is are there any long term side effects? As far as price goes-when I have a migraine-the way I used to feel before Amerge-I would gladly hand someone 3o dollars or more if they told me they could get rid of that pain-and that is what Amerge does for me-and so I agree it is a lot-but I wouldn't live without it! To answer the person above who wonders if their headache is a true migraine, since mine never get to the really bad stage anymore, I have asked my doctor the same question, and she said if it works it was a migraine. It sure works!


I have been taking Amerge for about 2 years. I could not survive without it. It is very expensive but worth every dime. Luckily my doctor started me out on this medication. It really works...


Even though it has already been said, Amerge -- more so than any of the other migraine medications I have tried -- is extremely effective. It is also the only migraine medication I have tried that doesn't cause the neck/throat pain and jaw soreness. Because of the steep price, I only take it for the worst migraines, but it has never failed me.


I just started amerge today for extremely bad migrains, it has worked yet, it still is killing me. How long do I have to wait till it takes affect?? ANybody know. This was my first dose. and it's been a couple of hours no relief at all. ??????

Cluster Headache relief

I am a nurse who has suffered with Cluster headaches for years - about 5 years ago a doctor suggested I try Amerge since Imitrex wasn't helping. Amerge has made my life so much more productive and my quality of life has much improved. I take 2 Amerge as soon as I wake up at 2 or 3 AM and by morning I can function as a real human being. Years previous these pounding behind one eye headaches would ruin at least 3 days of my life - I worked anyway knowing that nothing helped - but I didn't function very well. Amerge has allowed me to get back into life right away - once in awhile I have to repeat the dose during an episode - no matter the cost Amerge is worth the relief I experience. I believe it is worth a try for other "Cluster headache" sufferes to try!

No Subject

Love love love it! The only thing that doesn't give me horrible side effects.

Heart Attack

Beware of this drug. After taking one amerge pill perscribed my my doctor, I experienced a heart attack. I had no cardiac problems previously, as a 40 yr old male, that does not drink, smoke and is in shape and no other risk factors. The tripan manufacturers are trying to push this drug and minimize the serious risks as well as some doctors. My doctor told me about none of the risks of this drug.

Excellent Medicine for Migranes!

I'm very fortunate that my insurance pays all but $10.00 for 30 tablets of amerge. I can't believe how much better I feel now that my headache is gone and I can control it if it comes back! Great pill and I'm not big on taking pills!

No Subject

I tried Amerge today after a headache that was going on 3 hours. I don't believe my headaches are classical migraines, but when I get 1 of these I know they will last well into the night. Was unsure at first if I should try the sample my Dr. gave me month's ago, but was tired of the pain. I took one 2.5 tab along with a analgesic and layed down with a cold pack on my head. Woke up 2 hours later and the headache was gone. Would definetly try again.

No Subject

i have not used Amerge yet, but was wondering if there are any side affects of taking it when you think you are getting a migraine, but then it ends up being a normal headache?

No Subject

I suffer from Menstrual Migraines. Amerge has been wonderful for me! When my doctor gave me a sample, I was skeptical about trying it. Nothing else had worked to alleviate the pain I felt pretty much every month. However, it worked! Once I feel a migraine coming, I take Amerge and it subsides within 2 to 4 hours. Relief never felt so good.

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