Apokyn

The below information on Apokyn has been taken from official FDA sources, but we cannot guarantee it's accuracy. Please use this site for educational purposes only. This site does not replace a proper discussion with your doctor.


    Brand Name:Apokyn
    Generic:Apomorphine Hydrochloride
    Availability:Prescription
This drug was approved by the FDA in one form or another on:
2004-04-20 ,
This drug is made in one form or another by the following companies:
Mylan Bertek Pharmaceuticals, Inc.
This drug is available in the following forms:
Injectables
View the actual FDA approved label for this drug at the following links:
http://www.fda.gov/cder/foi/label/2004/21264_apokyn_lbl.pdf

About Apokyn

Apokyn is used by injection, as needed, only to treat loss of control of body movements in people with advanced Parkinson’s disease (PD). This condition is also called hypomobility or “off” episodes. An "off" episode may include symptoms such as muscle stiffness, slow movements, and difficulty starting movements. Apokyn may improve your ability to control your movements when it is used during an “off” episode. This may help you walk, talk, or move around easier. Apokyn is not used to prevent “off” episodes. Apokyn does not take the place of your other medicines for PD.

Precautions for Apokyn

  • Do not drink alcohol or take medicines that make you sleepy while you are taking Apokyn.
  • Do not drive a car, operate machinery, or do anything that might put you at risk of getting hurt until you know how Apokyn affects you. Apokyn may cause dizziness or fainting. Do not change your body position too fast. Get up slowly from sitting or lying. Apokyn can lower your blood pressure and cause dizziness or fainting.

Side Effects of Apokyn

Some common side effects with Apokyn include:

  • heart problems (shortness of breath, fast heartbeat, chest pain)
  • severe nausea and vomiting
  • sleepiness or falling asleep during the day
  • falls sudden
  • uncontrolled movements
  • dizziness
  • hallucinations
  • depression
  • headache
  • injection site reactions
  • swelling of arms/legs
  • increased sweating
  • flushing
  • paleness
  • yawning
  • runny nose

Who Should Not Take Apokyn

Do not take Apokyn if you are:

  • allergic to Apokyn or to any of its ingredients. Apokyn contains a sulfite called metabisulfite. Sulfites can cause severe, life-threatening allergic reactions in some people, especially in people with asthma.
  • being treated with certain drugs to treat nausea and vomiting or irritable bowel syndrome. These medications (including, for example, ondansetron, granisetron, dolasetron, palonosetron, and alosetron) are called 5HT3 antagonists or blockers. People taking this type of drug together with apomorphine have had severely low blood pressure and lost consciousness or “blacked out.”
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