The below information on Azilect has been taken from official FDA sources, but we cannot guarantee it's accuracy. Please use this site for educational purposes only. This site does not replace a proper discussion with your doctor.

    Brand Name:Azilect
    Generic:Rasagiline Mesylate
This drug was approved by the FDA in one form or another on:
2006-05-16 ,
This drug is made in one form or another by the following companies:
This drug is available in the following forms:
View the actual FDA approved label for this drug at the following links:

About Azilect

Azilect is a prescription medicine used to treat the signs and symptoms of Parkinson’s disease in adults. Azilect is used alone or with the medicine levodopa.

Azilect has not been studied in children.

Side Effects of Azilect

Azilect may cause serious and life-threatening side effects when taken:

  • with many other medicines
  • with foods or drinks that contain tyramine. Ask your healthcare professional for a list of tyramine-containing foods and drinks that should be avoided with Azilect.

Call your health care professionalright away if you have any of these serious side effects:

  • severe headache
  • blurred vision, large pupils, vision changes, sudden sensitivity to light
  • trouble thinking
  • fainting or loss of consciousness
  • seizure
  • signs or symptoms of a stroke
  • irregular heartbeat
  • chest pain
  • neck stiffness or soreness
  • unexplained nausea or vomiting
  • sweating or clammy skin (sometimes with fever)

Azilect may also cause the following serious side effects:

  • A skin cancer called melanoma: People with Parkinson’s disease may have a higher chance of developing melanoma. It is not known if this higher chance is related to Parkinson’s disease or to the medicines used to treat the disease. You should have regular check-ups to monitor for melanoma.
  • difficulty with movements: You may have more involuntary movement or difficulty in performing voluntary movements if you take Azilect with levodopa.
  • low blood pressure: Azilect may cause a sudden fall in blood pressure when standing up too fast. This can lead to dizziness or lightheadedness. This may happen more often during the first 2 months of treatment. Low blood pressure is also more likely to happen if you are also taking levodopa.
  • hallucinations: Hearing or seeing things that are not there. Hallucinations are more likely to happen if you are also taking levodopa.
  • other common side effects that may happen with Azilect include:
    • dizziness
    • joint pain
    • heartburn
    • nausea and vomiting
    • fever
    • muscle pain
    • dry mouth
    • stomach area pain
    • falls or accidental injury
    • headache
    • weight loss
    • loss of appetite
    • sleepiness
    • constipation

Who Should Not Take Azilect

Do not take Azilect if you:

  • have an adrenal gland tumor called a pheochromocytoma
  • are schedule for surgery. Azilect should be stopped 14 days before surgery.

Interactions with Azilect

Azilect and certain other medicines may interact with each other. Tell your healthcare professional about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Know the medicines you take. Keep a list of them with you to show your healthcare professional. Especially tell your healthcare professional if you take:

  • antidepressants
  • appetite suppressants
  • bronchodilators
  • cough/cold medicines
  • drugs for Attention Deficit Hyperactivity Disorder
  • certain drugs for glaucoma
  • certain herbal products
  • certain drugs for high blood pressure
  • certain pain medicines
  • certain migraine medicines
  • certain muscle relaxants
  • levodopa/carbidopa
  • ciprofloxacin
  • theophylline

Azilect may cause serious and life-threatening side effects when taken with foods or drinks that contain tyramine.

Foods, drinks, and dietary supplements which have tyramine are:

  • Air dried, aged and fermented meats, sausages and salamis (including cacciatore, hard salami and mortadella); pickled herring; any spoiled or improperly stored meat (such as beef, chicken or fish) or animal livers, (e.g., foods that have undergone changes in coloration, odor, or become moldy)
  • Broad bean pods (fava bean pods)
  • Aged cheeses
  • All varieties of tap beer and beers that have not been pasteurized so as to allow for ongoing fermentation
  • red wines
  • Concentrated yeast extract (e.g. Marmite), sauerkraut, most soybean products (including soy sauce and tofu)
  • OTC supplements containing tyramine
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Recent Forum Posts on Azilect

Azilect and tyramine

Hi, This is my first post and I have a bunch of questions. A little background. I was recently diagnosed with early stages of Parkinson's and my Dr put me on Amantadine 100mg and one week later wants me to start taking Azilect 1mg also. I picked up my prescription of Azilect 1mg today. Should I take it with or without food, and what benefit should it give me? How careful do I have to be about foods containing tyramine? It seems there are so many foods: Chocolate Teriyaki or soy sauce in what amounts Beer or whisky Bouillon and other soup cubes, canned soups Cheeses Many fruits (but not all) contain tyramine, including bananas, figs, grapes, oranges, pineapples and plums Many things have some tyramine and a few have a lot in them. Do I have to stay away from all of them? I know my Dr. should answer these but he hasn't so any help would be greatly appreciated. Thanks, Jeff

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