The below information on Cymbalta has been taken from official FDA sources, but we cannot guarantee it's accuracy. Please use this site for educational purposes only. This site does not replace a proper discussion with your doctor.

    Brand Name:Cymbalta
    Generic:Duloxetine Hydrochloride
This drug was approved by the FDA in one form or another on:
2004-08-03 ,
This drug is made in one form or another by the following companies:
Eli Lilly and Company
This drug is available in the following forms:
Capsules, Delayed Release Pellets
View the actual FDA approved label for this drug at the following links:

About Cymbalta

Cymbalta is in a class of medicines called serotonin and norepinephrine reuptake inhibitors (SNRIs). Cymbalta is used to treat depression.

Side Effects of Cymbalta

  • Possible life-threatening serotonin syndrome when used with triptan medicines.
  • Suicidal thoughts or actions: Persons taking Cymbalta may be more likely to think about killing themselves or actually try to do so, especially when Cymbalta is first started or the dose is changed. People close to persons taking Cymbalta can help by paying attention to changes in user’s moods or actions. Contact your healthcare professional right away if someone using Cymbalta talks about or shows signs of killing him or herself. If you are taking Cymbalta yourself and you start thinking about killing yourself, tell your healthcare professional about this side effect right away.
  • Stopping Cymbalta: Do not stop taking Cymbalta suddenly because you could get side effects. Your healthcare professional will slowly decrease your dose.
  • Possible liver damage: Cymbalta may cause liver damage. Do not drink alcohol while taking Cymbalta because this can make liver damage worse.
  • Blood pressure: Your blood pressure may increase.
  • Mania: You may become unusually hyperactive, excitable or elated.
  • Seizures: You may experience a seizure (convulsion), even if you are not taking Cymbalta close in time with a MAOI.
  • Pregnancy: Tell your healthcare professional if you are or may be pregnant because babies delivered to mothers taking Cymbalta late in pregnancy have developed problems, such as difficulty breathing and feeding.
  • Sexual problems: You may have problems with impotence (erectile dysfunction), abnormal ejaculation, difficulty reaching orgasm, or decreased libido (sexual desire).
  • Other side effects include nausea, dry mouth, constipation, decreased appetite, fatigue, sleepiness, and increased sweating.
  • Tell your healthcare professional about all your medical conditions, especially if you have liver or kidney disease, or glaucoma. Tell your healthcare professional if you are breast-feeding or plan to breast-feed your baby.

Who Should Not Take Cymbalta

Never take Cymbalta if you are taking another drug used to treat depression, called a Monoamine Oxidase Inhibitor (MAOI), or if you have stopped taking an MAOI in the last 14 days. Taking Cymbalta close in time to an MAOI can result in serious, sometimes fatal, reactions, including:

  • High body temperature
  • Coma
  • Seizures (convulsions)

MAOI drugs include Nardil (phenelzine sulfate), Parnate (tranylcypromine sulfate), Marplan (isocarboxazid), and other brands.

Never take Cymbalta if you have uncontrolled narrow-angle glaucoma (disease causing increased pressure in the eye).

Do not take Cymbalta if you have serious kidney or liver disease or drink alcohol excessively.

Interactions with Cymbalta

  • Cymbalta may interact with medicines other than the ones already mentioned in this information sheet, causing serious side effects. Tell your healthcare professional about all medicines, vitamins, and herbal supplements you take, especially those used to treat anxiety, mental illness, depression, infections, or heart problems.
  • Do not drink alcohol while taking Cymbalta.
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Recent Forum Posts on Cymbalta


After 14 TIA's. (Mimi strokes) Many trips to hospital 1000's 0 of $'s in medical bills, tears, fears etc. doctor finally determined it was the Cymbalt causing my problems. Stay away from this drug.

sleepless in n.j.

hi, i have been taking cymbalta and ablify for 2 months. i don't know if abilify is what is causing nightmares when i finally do sleep.on cymbalta noticed i havn't been crying as much and now can go out alittle without freaking.side effects are a little scary to me.has anyone else had closing of the throat. not sure if this is from abilify.hope soon i will find myself again.finally get a good night sleep.:eek:


i have been on every antidepressant..prozac, zoloft, effexor, celexa, lexapro, serzone, wellbutrin, wellbutrin sr. and cymbalta is the only one that has provided relief of my depression..i was taking 60mg. daily but increased it to 90mg. last week because i was in a car accident and i kept having flashbacks of it. it has worked well with that..the only side effects is nausea (for the first couple days), lack of appetite, and no sex drive.
but it is worth it since my depression was really when i step outside..everything is colorful again. before everything seemed gray and bleak...not anymore
i would ask anyone that is not receiving benefits with their current medication to try goes great with wellburin sr. (to help with the low sex drive), but i take dexedrine because of my adhd

No Subject

My experience with Cymbalta was been extremely good. I have Multiple Sclerosis (with pain) and depression. I take Cymbalta for the depression and because of it's properties to help with neuropathic pain. For me it works great for both without any noticeable side effects.

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