Indocin

The below information on Indocin has been taken from official FDA sources, but we cannot guarantee it's accuracy. Please use this site for educational purposes only. This site does not replace a proper discussion with your doctor.


    Brand Name:Indocin
    Generic:Indomethacin
    Availability:Prescription
This drug was approved by the FDA in one form or another on:
1985-10-10 ,
This drug is made in one form or another by the following companies:
Merck & Co., Inc.
This drug is available in the following forms:
Oral Suspensions
View the actual FDA approved label for this drug at the following links:
http://www.fda.gov/cder/foi/label/2007/016059s097,017814s040,018332s030lbl.pdf

About Indocin

Indocin is used for:

Treating moderate to severe rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. It is used to treat gout or certain types of bursitis and tendonitis. It may also be used for other conditions as determined by your doctor.

Indocin is an NSAID. Exactly how it works is not known. It may block certain substances in the body that are linked to inflammation. NSAIDs treat the symptoms of pain and inflammation. They do not treat the disease that causes those symptoms.

Side Effects of Indocin

Possible side effects of Indocin :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

  • Constipation;
  • diarrhea;
  • dizziness;
  • drowsiness;
  • gas;
  • headache;
  • heartburn;
  • nausea;
  • stomach upset.
Seek medical attention right away if any of these SEVERE side effects occur:
  • Severe allergic reactions (rash; hives; itching; trouble breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue);
  • blood in the urine;
  • bloody or black, tarry stools;
  • change in the amount of urine produced;
  • chest pain;
  • confusion;
  • dark urine;
  • depression;
  • fainting; fast or irregular heartbeat;
  • fever, chills, or persistent sore throat;
  • mental or mood changes;
  • numbness of an arm or leg;
  • one-sided weakness;
  • rectal bleeding;
  • red, swollen, blistered, or peeling skin;
  • ringing in the ears;
  • seizures;
  • severe headache or dizziness;
  • severe or persistent stomach pain or nausea;
  • severe vomiting;
  • shortness of breath;
  • sudden or unexplained weight gain;
  • swelling of hands, legs, or feet;
  • unusual bruising or bleeding;
  • unusual joint or muscle pain;
  • unusual tiredness or weakness;
  • unusual vaginal bleeding;
  • vision or speech changes;
  • vomit that looks like coffee grounds;
  • yellowing of the skin or eyes.

Who Should Not Take Indocin

Do NOT use Indocin if:

  • you are allergic to any ingredient in Indocin
  • you have had a severe allergic reaction (eg, severe rash, hives, trouble breathing, growths in the nose, dizziness) to aspirin or an NSAID (eg, ibuprofen, celecoxib)
  • you have recently had or will be having bypass heart surgery
  • you are taking diflunisal, another NSAID (eg, ibuprofen), or triamterene
  • you are in the last 3 months of pregnancy

Contact your doctor or health care provider right away if any of these apply to you.

Interactions with Indocin

Some MEDICINES MAY INTERACT with Indocin . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Anticoagulants (eg, warfarin), corticosteroids (eg, prednisone), diflunisal, heparin, other NSAIDs (eg, ibuprofen), salicylates (eg, aspirin), or selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine) because the risk of stomach bleeding may be increased
  • Potassium-sparing diuretics (eg, spironolactone, triamterene) because the risk of kidney problems or increased blood potassium levels may be increased
  • Cyclophosphamide because low blood sodium levels may occur
  • Probenecid because it may increase the risk of Indocin's side effects
  • Cyclosporine, digoxin, lithium, methotrexate, quinolones (eg, ciprofloxacin), or sulfonylureas (eg, glipizide) because the risk of their side effects may be increased by Indocin
  • Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril), angiotensin receptor blockers (eg, losartan), beta-blockers (eg, propranolol), or diuretics (eg, furosemide, hydrochlorothiazide) because their effectiveness may be decreased by Indocin
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