The below information on Lotronex has been taken from official FDA sources, but we cannot guarantee it's accuracy. Please use this site for educational purposes only. This site does not replace a proper discussion with your doctor.

    Brand Name:Lotronex
    Generic:Alosetron Hydrochloride
This drug was approved by the FDA in one form or another on:
2000-02-09 ,
This drug is made in one form or another by the following companies:
This drug is available in the following forms:
View the actual FDA approved label for this drug at the following links:

About Lotronex

LOTRONEX is a medicine that slows the movement of stools (bowel movements) through the bowels. LOTRONEX does not cure IBS and it will not help every person who takes it. For those who are helped, LOTRONEX reduces lower abdominal (stomach area) pain, abdominal discomfort, urgency (sudden need to have a bowel movement), and diarrhea of IBS. If you stop taking LOTRONEX, your IBS symptoms may return within 1 or 2 weeks.

Side Effects of Lotronex

Constipation is the most common side effect of LOTRONEX. A few patients may develop serious intestinal side effects.

Who Should Not Take Lotronex

LOTRONEX is not right for everyone. It is only for women with troublesome diarrhea-predominant IBS.

  1. Do not start taking LOTRONEX if you are constipated
  2. Do not ever take LOTRONEX if you
    • are constipated most of the time
    • have ever had severe constipation or a serious problem from constipation
    • have ever had ischemic colitis
    • have ever had Crohn's Disease or ulcerative colitis
    • have active diverticulitis
    • are allergic to LOTRONEX or any of its ingredients.

If you take LOTRONEX under these conditions, you increase your risk of getting serious side effects.

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