The below information on Lunesta has been taken from official FDA sources, but we cannot guarantee it's accuracy. Please use this site for educational purposes only. This site does not replace a proper discussion with your doctor.

    Brand Name:Lunesta
This drug was approved by the FDA in one form or another on:
2004-12-15 ,
This drug is made in one form or another by the following companies:
Sepracor Inc.
This drug is available in the following forms:
View the actual FDA approved label for this drug at the following links:

About Lunesta

Lunesta is used for:

Treating sleeping problems with symptoms such as difficulty falling asleep, difficulty staying asleep during the night, and or waking up too early in the morning.

Lunesta is a hypnotic or "sleep medicine." It works by helping to increase certain natural chemicals in acting on certain parts of the brain that cause to help you sleep better.

Side Effects of Lunesta

Possible side effects of Lunesta :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

  • Anxiety;
  • decrease in sexual desire;
  • difficulty with coordination;
  • dizziness;
  • drowsiness;
  • dry mouth;
  • headache;
  • indigestion;
  • lightheadedness;
  • nausea;
  • nervousness;
  • unpleasant taste;
  • vomiting.
Seek medical attention right away if any of these SEVERE side effects occur:
  • Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue);
  • aggressive behavior;
  • breast growth;
  • chest pain;
  • confusion;
  • depression;
  • hallucinations;
  • memory problems (such as amnesia);
  • painful menstrual periods;
  • seizures;
  • severe mood swings;
  • suicidal thoughts;
  • swelling of hands or feet;
  • symptoms of infection (eg, fever, sore throat, and sinus or chest congestion);
  • unusual or disturbing thoughts.

Who Should Not Take Lunesta

Do NOT use Lunesta if:

  • you are allergic to any ingredient in Lunesta

Contact your doctor or health care provider right away if any of these apply to you.

Interactions with Lunesta

Some MEDICINES MAY INTERACT with Lunesta . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Lorazepam or rifampicin because they may decrease Lunesta's effectiveness
  • Certain antibiotics (eg, clarithromycin, troleandomycin), antifungal medicines (eg, ketoconazole, itraconazole), medicines for HIV infection (eg, nelfinavir, ritonavir), nefazodone, or olanzapine because they may increase the risk of Lunesta's side effects
  • Antidepressants (eg, amitriptyline), antihistamines (eg, diphenhydramine, chlorpheniramine), medicine for mental or mood disorders (eg, thioridazine, haloperidol), or medicines for seizures (eg, phenytoin, carbamazepine, phenobarbital) because the risk of their side effects, including drowsiness and incoordination, may be increased by Lunesta
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Recent Forum Posts on Lunesta

Lunesta and Remeron and tons of other drugs

I'm hoping that one of you readers can share your experiences and any advice that you may have with the effects of combining Lunesta, Remeron, and a cocktail of other drugs. I greatly appreciate anything that you can contribute; I feel that I may have lost over a year of my life as a result of being perscribed a bad concotion of meds. For 5 years I took the combo of 20mg Remeron, 60mg Lexapro, and Ativan as needed (I hate to fly but was doing it often). I was happy as a clam. Nothing rattled me and I was pretty much in a state of bliss for that entire time. While I have been a chronic insomniac all of my life, I was sleeping very well w/ the Remeron. Yes, I gained weight but at the time I couldn't care less. Like I said, I was HAPPY! After 5 years I wondered if I didn't need the meds anymore. I figured that I was a very happy person now and could stop taking these drugs. So I asked my former psychiatrist to help me step down from Remeron. Becasue it had worked as a sleep aid for me and I was starting to have sleep trouble again, she perscribed 6 mg of Lunseta. These 2 drugs weer overlapped for aprox. 3 weeks during the month of March last year. My last dosage of Remeron was on 29 Mar. With a week or less I started having very short seizures. Across the course of 3 days I had 27 in total; I have not experince these again since. Having done some research on the web it appears that the best description for them is myoclonic seizures; it felt as if I was pushed forward by a force that was uniform across by back, then all of my muscles tightened around my bones, and then they relaxed. This lasted for a matter of seconds although it felt like years. At the time I was also taking 200 mg of Lamictal, and 15 mg of Buspirone. My symptoms grew steadily worse and worse after the seizures. At one point I couldn't even drive. I had major dizziness, loss of balance, trouble remembering words, trouble reading and at times the inability to do simple mathmatics. I had terrible short & long term memory loss, 2 audio hallucinations,and was highly light and sound sensitive (flickering lights killed me). I would get a pins & needles sensation in my face, especially when looking over my shoulders or bending down. I couldn't understand what people were saying on TV or in movies - it seemed like hey were talking a mile a minute even though other people in the room had no problem understanding them. The worst symptom was the feeling that a layer between my skull and scalp was shifting in small, periodic movements - like the hands of a clock. These symptoms have subsided over time (started to do so in Oct of last year), and the only one that I still struggle with - big time - is short term memory loss. I'm currently taking 3 mg Lunesta (slowing decreased from 6mg), 400 mg Lamictal, 40 mg Buspirone, 30mg Lexapro, and 1.0 Ativan as needed. I've had a full nuerological work up done and there isn't anything wrong with the old gourd. Everything seems to point to the drugs. Any insights??

No Subject

Do not take Benadryl if you are on Lunesta, even if you didn't take a Lunesta that night. I made this mistake, and began having trouble breathing. I felt that as I dosed off, my breathing stopped, thus I was forced to stay awake until it wore off. Probably should have went to the emergency center..

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