The below information on Prialt has been taken from official FDA sources, but we cannot guarantee it's accuracy. Please use this site for educational purposes only. This site does not replace a proper discussion with your doctor.

    Brand Name:Prialt
This drug was approved by the FDA in one form or another on:
2004-12-28 ,
This drug is made in one form or another by the following companies:
Elan Pharms
This drug is available in the following forms:
Intrathecal Injections
View the actual FDA approved label for this drug at the following links:

About Prialt

Prialt is a prescription medicine that a doctor injects into your spinal fluid through a special device. It is used to treat severe chronic pain in adults who cannot take other treatments or when other treatments have not worked. Other treatments include systemic pain medicines, treatments used in combination with pain medicines, or morphine injected into the spinal fluid.

The safety and effectiveness of Prialt in pediatric patients has not been established.

Side Effects of Prialt

Prialt can cause serious problems that you should tell your doctor or health care professional about immediately such as:

  • Severe Psychiatric Symptoms or Neurological Impairment including changes in mood or perception (hallucinations, including unusual sensations in the mouth and throat), changes and slowing in thinking, depression or suicidal thoughts, confusion, memory impairment, speech disorder, or inability to eat.
  • Unconsciousness or Reduced Mental Alertness indicated by changes in mental status (tiredness, confusion, disorientation, or decreased alertness). Some people have lost consciousness while being treated with Prialt. It may not be safe for you to engage in hazardous activity requiring complete mental alertness or motor coordination such as operating machinery or driving a motor vehicle during treatment.
  • Meningitis or Other Infections indicated by signs and symptoms that include but are not limited to fever, headache, stiff neck, altered mental status (tiredness, confusion, disorientation or decreased alertness), nausea or vomiting, and sometimes seizures.
  • Serious muscle damage. Your doctor should regularly monitor you for muscle damage by doing a blood test to check foran increase in Serum Creatine Kinase (CK). Increased CK levels in the blood may mean there is damage to your muscles. High levels of CK in the blood can damage your kidneys. Call your doctor right away if you have new muscle pain, soreness, weakness, or your urine is dark in color.
  • The most common side effects with Prialt are dizziness, nausea, confusion, headache, sleepiness, problems with vision, weakness, and pain.

Who Should Not Take Prialt

You should not be given Prialt if you:

  • are allergic to Prialt or any ingredient in it.
  • have a condition or are receiving a treatment that would cause an injection in your spinal fluid to be unsafe.
  • have or had a mental illness called psychosis.
  • have an infection at the device injection site, uncontrolled bleeding problems, or a blockage in your spinal cord area.

Interactions with Prialt

Prialt and certain other medicines can interact and cause serious side effects. Tell your doctor or healthcare professional about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Your doctor may have to adjust your dose of Prialt or watch you more closely if you take other medicines that affect your nervous system.

Search the Web for more info:  

Recent Forum Posts on Prialt

Do Any Of You Make It Through A Full Night Sleep??

Looking for some way to make it through a 6-8 hour sleep?? I have diabetic neuropathy, cronic pain in both feet and cant sleep more than 2-4 hours and wake up ready to did, taking IM 4mg Dilaudid for the pain and 2 mg Xanax for sleep and still cant make it through a night, very depressed and extremely tired, family life is getting harder and harder, moods and hatred of life??Anyone that can help please do. Any suggestions would be wonderful, really need some input!

Looking For People That Are On Prialt From Dilaudid

I Am A Diabetic With Extreme Cronic Neuropathy Of Both Feet, At The End Of My Wits, Been Through Every Drug, Anti Depressants, Lyrica, Gabrapenton, Oxy, Loritab, Ect Ect On Im Dilaudid And Still Not Going Below A 5-6 Daily And Most Of The Time A 7-9. My Doctor Says Prialt Is My Final Hope, Anyone Gone This Route?? Please Help Me With Your Insight.

has anyone experienced this????Need Help ASAP

Hello, I am trying to find out as much info as possible. My brother-in-law has been in the hospital for almost 5 weeks due to severe paranoia, and delusions. He was initially hospitalized for the delusions and paranoia and now after 4 weeks of the medicine being out of his pump, is suffereing from severe paranoia. He is 30 years old and has had chronic back pain from an accident at 12. Please let me know if you have heard any info that might help give our family a timeline in recovering.

Considering Prialt

Hello, I am a 53 y/o retired (forced) veterinarian considering Prialt. I have had back and neck surgeries due to DJD. I experience severe back and leg pain bilaterally and can hardly walk some days. I am on Lyrica, Oxycontin, hydocodone, Cymbalta to name a few. I am extremely worried about the side effects of Prialt. I had an adjustment period with Lyrica, but tolerate it well now. Any information or personal experiences would be welcome.

dilaudin-prialt interactions

Meditronic pain pump- already have dilaudid 22mg intrathecally per day.. want to decrease the dilaudid and replace it with prialt? Want to know if there are any withdrawls possible. Or if anyone has experienced any problems with this. Have had chronic pain since 5/5/85..Several surguries. some pretty major last two on the spinal cord itself..Need relief from the pain. Running out of options..Need advice...Don't want to spend the rest of my life in pain..with no relief and lying in bed..Help...

Post a New Comment/Question on Prialt in our forums.