Priftin

The below information on Priftin has been taken from official FDA sources, but we cannot guarantee it's accuracy. Please use this site for educational purposes only. This site does not replace a proper discussion with your doctor.


    Brand Name:Priftin
    Generic:Rifapentine
    Availability:Prescription
This drug was approved by the FDA in one form or another on:
1998-06-22 ,
This drug is made in one form or another by the following companies:
Sanofi Aventis US
This drug is available in the following forms:
Tablets
View the actual FDA approved label for this drug at the following links:
http://www.fda.gov/cder/foi/nda/2000/21024s5_Priftin_prntlbl.pdf

About Priftin

Priftin is an antibiotic used to treat pulmonary tuberculosis (TB). Priftin must only be used in combination with at least one other anti-TB drug prescribed for your condition. You must take Priftin twice a week for 2 months with no less that 3 days (72 hours) between doses, plus other daily medications as directed during this intensive phase of the treatment. It is critical that you not miss even one dose of Priftin or your other medications during this 2-month intensive phase of treatment to make sure that TB disappears from the saliva and to make sure that TB does not return.

After the first 2 months, you must take Priftin once a week in combination with at least another anti-TB drug prescribed for your condition.

Experience using Priftin with HIV - positive patients is limited. If you are HIV - positive, you may require more frequent doses; consult your health care provider.

Precautions for Priftin

  • It is very important to take your medicines exactly as prescribed by your health care provider for the entire time that you are being treated. It is especially important not to skip doses. Otherwise, TB can return.
  • If you begin having severe and/or constant diarrhea, stop taking Priftin immediately and contact your health care provider for treatment.
  • Priftin has been shown to interact with certain drugs (protease inhibitors) used to treat HIV-infection.
  • If you have a history of poor nutrition, alcoholism, diabetes, or you are a teenager; your health care provider may want you to add vitamin B6 as a supplement to your diet.
  • Priftin may affect the reliability of birth control pills, so other methods of birth control should be used while taking Priftin.
  • If you are in the late stages of pregnancy, your health care provider may check your blood for clotting ability.

Side Effects of Priftin

Because Priftin is never taken alone, the following list of side effects may be shared with any of the combination drug treatments used in clinical trials. They are:

  • Blood in urine
  • Rash
  • Itchiness
  • Skin breakouts
  • Loss of appetite
  • Loss of iron in the blood
  • Joint pain
  • Pain
  • Nausea
  • Vomiting

You may see a red-orange color change to your body fluids (e.g., urine, sweat, spit, tears, and breast milk), or tissues (e.g., skin, teeth, and tongue).

If you wear contact lenses or dentures, they may be permanently stained this red-orange color.

Who Should Not Take Priftin

You should not take Priftin if you have:

  • a history of allergic reaction to any of the rifamycins (e.g., rifampin and rifabutin)
  • a history of porphyria
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