The below information on Prozac has been taken from official FDA sources, but we cannot guarantee it's accuracy. Please use this site for educational purposes only. This site does not replace a proper discussion with your doctor.
|This drug was approved by the FDA in one form or another on:|
|This drug is made in one form or another by the following companies:|
Eli Lilly and Company
|This drug is available in the following forms:|
Capsules and Oral Solutions
|View the actual FDA approved label for this drug at the following links:|
Prozac is in a class of medicines called selective serotonin reuptake inhibitors (SSRIs). Prozac is used to treat Depression, Obsessive-Compulsive Disorder (OCD), Bulemia Nervosa, and Panic Disorder.
Side Effects of Prozac
- Possible life-threatening serotonin syndrome when used with triptan medicines.
- Infant persistent pulmonary hypertension.
- Suicidal thoughts or actions: Persons taking Prozac may be more likely to think about killing themselves or actually try to do so, especially when Prozac is first started or the dose is changed. People close to persons taking Prozac can help by paying attention to changes in user’s moods or actions. Contact your healthcare professional right away if someone using Prozac talks about or shows signs of killing him or herself. If you are taking Prozac yourself and you start thinking about killing yourself, tell your healthcare professional about this side effect right away.
- Stopping Prozac: Do not stop taking Prozac suddenly because you could get side effects. Your healthcare professional will slowly decrease your dose.
- Rash and possible allergic reactions: Prozac may cause serious skin, lung and allergic-type reactions. Contact your healthcare professional right away if you get a skin rash or hives, have problems breathing, or get swelling of your tongue, lips, or throat.
- Bleeding problems: Prozac may cause bleeding problems, especially if taken with aspirin, NSAIDs (nonsteroidal anti-inflammatory drugs, such as ibuprofen and naproxen), or other drugs that affect bleeding.
- Mania: You may become unusually hyperactive, excitable or elated.
- Seizures: You may experience a seizure (convulsion), even if you are not taking Prozac close in time with an MAOI.
- Weight loss: Prozac can cause weight loss. Children who take it for a long time should have their growth and body weight measured regularly.
- Pregnancy: Tell your healthcare professional if you are or may be pregnant. In addition to the issue described in the alert, babies delivered to mothers taking Prozac late in pregnancy have developed problems, such as difficulty breathing and feeding.
- Sexual problems: You may have problems with impotence (erectile dysfunction), abnormal ejaculation, difficulty reaching orgasm, or decreased libido (sexual desire).
- Other side effects include nausea, difficulty sleeping, anxiety, nervousness, and sleepiness.
- Tell your healthcare professional about all your medical conditions, especially if you have liver or heart disease, or diabetes. Tell your healthcare professional if you are breast-feeding or plan to breast-feed your baby.
Who Should Not Take Prozac
Never take Prozac if you are taking another drug used to treat depression, called a Monoamine Oxidase Inhibitor (MAOI), or if you have stopped taking an MAOI in the last 14 days. Taking Prozac close in time to an MAOI can result in serious, sometimes fatal, reactions, including:
- High body temperature
- Seizures (convulsions)
Do not take a MAOI within 5 weeks of stopping Prozac. MAOI drugs include Nardil (phenelzine sulfate), Parnate (tranylcypromine sulfate), Marplan (isocarboxazid), and other brands.
Never take Prozac if you are taking Mellaril (thioridazine), used to treat schizophrenia. Also, do not take Mellaril within 5 weeks of stopping Prozac. Taking Prozac close in time to Mellaril can result in serious heart beat problems.
Interactions with Prozac
- Do not take Prozac with Sarafem (Prozac hydrochloride), a drug used to treat PreMenstrual Dysphoric Disorder (PMDD), because they are very similar and you could get an overdose.
- Prozac may interact with medicines other than the ones already mentioned in this information sheet, causing serious side effects. Tell your healthcare professional about all medicines, vitamins, and herbal supplements you take, especially:
- Those that affect bleeding
- Those used to treat diabetes, seizures, anxiety, mental illness, or depression
- If you plan to drink alcohol, talk to your healthcare professional.
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