Sutent

The below information on Sutent has been taken from official FDA sources, but we cannot guarantee it's accuracy. Please use this site for educational purposes only. This site does not replace a proper discussion with your doctor.


    Brand Name:Sutent
    Generic:Sunitinib
    Availability:Prescription
This drug was approved by the FDA in one form or another on:
2006-01-26 ,
This drug is made in one form or another by the following companies:
CPPI CV, Pfizer
This drug is available in the following forms:
Capsules
View the actual FDA approved label for this drug at the following links:
http://www.fda.gov/cder/foi/2007/021938s002s003s004s005lbl.pdf

About Sutent

Sutent is a medicine used to treat adult patients with the following cancers:

  • a gastrointestinal stromal tumor after the disease worsened while taking another medicine called imatinib mesylate or when imatinib mesylate cannot be taken.
  • advanced renal cell carcinoma. At this time, it is not known whether Sutent will improve symptoms, or help patients with this disease live longer.

Sutent has not been studied in children.

Side Effects of Sutent

The following are the major possible risks and side effects of Sutent therapy:

  • harm to an unborn baby. Animal studies show death and birth defects happen in some unborn animal babies. There are no studies of Sutent in pregnant women. Women who can get pregnant should avoid becoming pregnant while taking Sutent.
  • a heart problem called left ventricular dysfunction, which can cause signs and symptoms of congestive heart failure.
  • stomach and digestive system problems. Some common stomach and digestive system side effects include:
  • diarrhea
  • nausea
  • mouth sores
  • indigestion
  • vomiting
  • an adrenal gland problem called adrenal insufficiency. This can make it harder for your body to handle the stress of surgery, an infection, or an injury. Tell your healthcare professional right away if you have an injury, an infection, or need surgery. Your adrenal function will have to be monitored closely.
  • skin and hair changes. Sutent may cause your skin to turn yellow and hair to lose color. Other possible skin side effects include:
  • dryness
  • thickness or cracking
  • blister or rash on the palms of hands and soles of the feet
  • Other common side effects that may occur with Sutent include:
  • tiredness
  • high blood pressure
  • bleeding
  • swelling
  • mouth pain and irritation
  • taste changes

Who Should Not Take Sutent

Do not take Sutent if you are allergic to Sutent or any of its ingredients.

Interactions with Sutent

Sutent and certain other medicines can interact with each other. Tell your healthcare professional about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Some medicines may affect how Sutent works or Sutent may affect how your other medicines work. Know the medicines you take. Keep a list of them with you to show your healthcare professional.

Especially tell your healthcare professional if you take or eat medicines or foods that may:

  • increase the amount of Sutent in the body, such as:
  • ketoconazole (Nizoral)
  • itraconazole (Sporanox)
  • clarithromycin (Biaxin, Biaxin XL, PrevPac)
  • atazanavir (Reyataz)
  • indinavir (Crixivan)
  • nefazodone (Serzone)
  • nelfinavir (Viracept)
  • ritonavir (Norvir, Kaletra)
  • saquinavir (Fortovase, Invirase)
  • telithromycin (Ketek)
  • voriconazole (VFend)
  • grapefruit
  • decrease the amount of Sutent in the body, such as:
  • dexamethasone
  • phenytoin (Dilantin, Phenytek)
  • carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Tegretol XR, Teril)
  • rifampin (Rifadin, Rifamate, Rifater, Rimactane)
  • rifabutin (Mycobutin)
  • rifapentin (Priftin)
  • phenobarbital
  • St. John’s Wort

Sutent and St. John's Wort should not be taken together.

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