Tolectin, Tolectin 600 and Tolectin DS

The below information on Tolectin, Tolectin 600 and Tolectin DS has been taken from official FDA sources, but we cannot guarantee it's accuracy. Please use this site for educational purposes only. This site does not replace a proper discussion with your doctor.


    Brand Name:Tolectin, Tolectin 600 and Tolectin DS
    Generic:Tolmetin Sodium
    Availability:Prescription
This drug was approved by the FDA in one form or another on:
1976-03-24 ,
This drug is made in one form or another by the following companies:
Ortho-McNeil Pharmaceutical, Inc.
This drug is available in the following forms:
Tablets and Capsules
View the actual FDA approved label for this drug at the following links:
http://www.fda.gov/cder/foi/label/2006/017628s067,018084s051lbl.pdf

About Tolectin, Tolectin 600 and Tolectin DS

Tolectin is used for:

Treating rheumatoid arthritis, osteoarthritis, or juvenile arthritis. It may also be used for other conditions as determined by your doctor.

Tolectin is an NSAID. Exactly how it works is not known. It may block certain substances in the body that are linked to inflammation. NSAIDs treat the symptoms of pain and inflammation. They do not treat the disease that causes those symptoms.

Side Effects of Tolectin, Tolectin 600 and Tolectin DS

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

  • Constipation;
  • diarrhea;
  • dizziness;
  • gas;
  • headache;
  • heartburn;
  • nausea;
  • stomach upset;
  • weakness.
Seek medical attention right away if any of these SEVERE side effects occur:
  • Severe allergic reactions (rash; hives; itching; trouble breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue);
  • bloody or black, tarry stools;
  • change in the amount of urine produced;
  • chest pain;
  • confusion;
  • dark urine;
  • depression;
  • fainting; fast or irregular heartbeat;
  • fever, chills, or persistent sore throat;
  • mental or mood changes;
  • numbness of an arm or leg;
  • one-sided weakness;
  • red, swollen, blistered, or peeling skin;
  • ringing in the ears;
  • seizures;
  • severe headache or dizziness;
  • severe or persistent stomach pain or nausea;
  • severe vomiting;
  • shortness of breath;
  • sudden or unexplained weight gain;
  • swelling of hands, legs, or feet;
  • unusual bruising or bleeding;
  • unusual joint or muscle pain;
  • unusual tiredness or weakness;
  • vision or speech changes;
  • vomit that looks like coffee grounds;
  • yellowing of the skin or eyes.

Who Should Not Take Tolectin, Tolectin 600 and Tolectin DS

Do NOT use Tolectin if:

  • you are allergic to any ingredient in Tolectin
  • you have had a severe allergic reaction (eg, severe rash, hives, trouble breathing, growths in the nose, dizziness) to aspirin or a nonsteroidal anti-inflammatory drug (NSAID) (eg, ibuprofen, celecoxib)
  • you have recently had or will be having bypass heart surgery
  • you are in the last 3 months of pregnancy

Interactions with Tolectin, Tolectin 600 and Tolectin DS

Some MEDICINES MAY INTERACT with Tolectin . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Anticoagulants (eg, warfarin), corticosteroids (eg, prednisone), heparin, salicylates (eg, aspirin), or selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine) because the risk of stomach bleeding may be increased
  • Probenecid because it may increase the risk of Tolectin's side effects
  • Cyclosporine, lithium, methotrexate, or quinolones (eg, ciprofloxacin) because the risk of their side effects may be increased by Tolectin
  • Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril), beta-blockers (eg, propranolol), or diuretics (eg, furosemide, hydrochlorothiazide) because their effectiveness may be decreased by Tolectin
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