The below information on Tygacil has been taken from official FDA sources, but we cannot guarantee it's accuracy. Please use this site for educational purposes only. This site does not replace a proper discussion with your doctor.

    Brand Name:Tygacil
This drug was approved by the FDA in one form or another on:
2005-06-15 ,
This drug is made in one form or another by the following companies:
Wyeth Pharmaceuticals, Inc.
This drug is available in the following forms:
Intravenous Injections
View the actual FDA approved label for this drug at the following links:

About Tygacil

  • Tygacil is a prescription antibiotic medicine injected into the vein for adults who have complicated skin or intra-abdominal infections caused by certain strains of bacteria.
  • Sometimes viruses, rather than bacteria, may infect the lungs and sinuses (for example, the common cold). Tygacil, like all other antibiotics, does not kill viruses.
  • Tygacil is in the glycylcycline class of antibiotics.
  • Tygacil should only be used to treat infections that are proven or strongly suspected to be caused by susceptible bacteria.
  • Tygacil has not been studied in children under 18 years of age.

Side Effects of Tygacil

Tygacil is structurally similar to tetracycline class antibiotics any may have similar side effects, such as:

  • Birth defects. Tygacil may cause birth defects when administered to pregnant women. Results of animal studies indicate that Tygacil crosses the placenta and is found in fetal tissues. Decreased birth weights and loss of pregnancy have been observed with Tygacil.
  • Change in tooth color. The use of Tygacil can cause a change in tooth color that does not go away. Tygacil should not be used during tooth development (last half of pregnancy and up until a child is 8 years old) unless other drugs are not likely to be effective or are contraindicated.
  • Pseudomembranous colitis. Tygacil, like other antibiotic medicines may cause pseudomembranous colitis. Tygacil can kill the healthy bacteria in your intestines, causing an overgrowth of bad bacteria in your colon that can range from mild to life-threatening. Tell your doctor right away if you get diarrhea.
  • The most common side effects with Tygacil are nausea, vomiting, and diarrhea.

Who Should Not Take Tygacil

Do not use Tygacil if you are allergic to tigecycline or any of the ingredients in Tygacil.

Interactions with Tygacil

Tell your doctor about all the medicines you are taking including prescription and nonprescription medicines, vitamins, and herbal supplements. Tygacil and certain other medicines may affect each other in the way they work in your body. Be sure to tell your doctor if you take:

  • warfarin (Coumadin), a blood thinner
  • birth control medications. Certain antibiotics may decrease the effectiveness of birth control medications.
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Recent Forum Posts on Tygacil


I have some question that why and how much Tygacil can rising BUN level?
My father take Tygacil to treat Pneumonia , Sputum c/s : Acinetobacter sp.
with multidrug resistance. His BUN rise to 130 , Cr 2.1 ; Now he has on tubation.
Please reply to me
Thank You for your kind
Wanida Kiatkongchuchai
4 Jan 08

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