The below information on Tysabri has been taken from official FDA sources, but we cannot guarantee it's accuracy. Please use this site for educational purposes only. This site does not replace a proper discussion with your doctor.

    Brand Name:Tysabri
This drug was approved by the FDA in one form or another on:
2004-11-23 ,
This drug is made in one form or another by the following companies:
Biogen Idec
This drug is available in the following forms:
View the actual FDA approved label for this drug at the following links:

About Tysabri

Tysabri is an intravenous (I.V.) medicine used to treat patients with relapsing forms of multiple sclerosis (MS) to reduce the number of relapses. A relapse is a time when new symptoms can appear and old symptoms come back or worsen. Relapses are followed by periods of time when no new symptoms occur (remission).

Tysabri is indicated for use as monotherapy, meaning it should not be used in combination with other immune system modifying drugs, and is for patients who have not responded adequately to, or cannot tolerate, other treatments for MS.

Side Effects of Tysabri

Tysabri increases the chance of patients getting a rare brain infection that usually causes death or severe disability. This infection is called progressive multifocal leukoencephalopathy (PML). PML usually happens in people with weakened immune systems. Because of the risk of PML, Tysabri is available only through a special restricted distribution program.

Tysabri may cause severe allergic reactions. These severe reactions usually happen within 2 hours of the start of the Tysabri infusion. Symptoms of a severe allergic reaction include an itchy swelling on the skin (hives), dizziness, fever, rash, shaking, nausea, flushing, low blood pressure, trouble breathing, and chest pain. People who have these severe reactions with Tysabri must have their infusion stopped right away, be treated for the reaction, and should not be treated with Tysabri again.

The serious side effects with Tysabri include:

  • serious infections, such as pneumonia
  • severe or life threatening allergic reactions

Other side effects may include infections, such as in the urinary tract or upper respiratory tract, headache, tiredness, depression, joint pain, diarrhea, and stomach area pain.

Interactions with Tysabri

Tell your healthcare professional about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your health care professional if you take:

  • corticosteroid medicines
  • any other medicines to treat multiple sclerosis, such as Interferon beta-1a (Avonex, Rebif); Interferon beta-1b (Betaseron), or glatiramer acetate (Copaxone).

These medicines and Tysabri may interact causing side effects or affect how each other work.

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