Valstar

The below information on Valstar has been taken from official FDA sources, but we cannot guarantee it's accuracy. Please use this site for educational purposes only. This site does not replace a proper discussion with your doctor.


    Brand Name:Valstar
    Generic:Valrubicin
    Availability:Prescription
This drug was approved by the FDA in one form or another on:
1998-09-25 ,
This drug is made in one form or another by the following companies:
Anthra Pharmaceuticals
This drug is available in the following forms:
Intravesical Sterile Solution
View the actual FDA approved label for this drug at the following links:
http://www.fda.gov/cder/foi/label/1998/20892lbl.pdf

About Valstar

Valstar is used for treatment of patients with BCG-resistant cancer of the urinary bladder for whom surgical removal of the bladder is not safe. Treatment with Valstar is through drug instillation into the urinary bladder.

Precautions for Valstar

You should discuss with your doctor the risks involved with delaying surgery, which could lead to bladder cancer spreading to other parts of your body (See Special Warnings).

Side effects from treatment with Valstar mainly involve irritable bladder symptoms (e.g., bladder spasm, spontaneous discharge of Valstar) occurring during treatment with Valstar or shortly after treatment. For the first 24 hours after treatment with Valstar, most patients have red-colored urine.

Tell your doctor immediately if you experience any continued irritable bladder symptoms or if you have red-colored urine after the first 24 hours following treatment.

Men and women of childbearing age should use an effective birth control method during the Valstar treatment period.

Women: Tell your doctor if you are trying to become pregnant, are already pregnant, or are breast-feeding. You should not become pregnant while being treated with Valstar.

Men: Do not engage in sexual activity that could lead to pregnancy while being treated with Valstar.

Side Effects of Valstar

Side effects with Valstar usually occur during or shortly after treatment and stop within 1 to 7 days after Valstar is removed from the bladder, including:

  • Urinating too often
  • Difficulty or pain during urination
  • Urge to urinate immediately
  • Bladder spasm
  • Blood in the urine
  • Bladder pain
  • Inability to control urination
  • Swelling of the bladder
  • Waking up at night to urinate
  • Burning sensation

Who Should Not Take Valstar

You should not be given Valstar if you have any of the following conditions:

  • Known reaction to other drugs that are similar to Valstar or Cremophor® EL
  • Urinary tract infection at the time of treatment
  • Small bladder capacity (i.e., unable to tolerate a 75ml instillation)
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