The below information on Vaprisol has been taken from official FDA sources, but we cannot guarantee it's accuracy. Please use this site for educational purposes only. This site does not replace a proper discussion with your doctor.

    Brand Name:Vaprisol
    Generic:Conivaptan Hydrochloride
This drug was approved by the FDA in one form or another on:
2005-12-29 ,2007-02-28 ,
This drug is made in one form or another by the following companies:
Astellas Pharma Inc.
This drug is available in the following forms:
View the actual FDA approved label for this drug at the following links:

About Vaprisol

Vaprisol is a medicine given in a vein (intravenous or I.V.) to raise low blood sodium levels in hospitalized patients with “euvolemic hyponatremia.” Euvolemic hyponatremia is when a patient has too little sodium in the bloodstream but a normal amount of fluid in the body.

Vaprisol should not be used to treat congestive heart failure.

Vaprisol has not been studied in children.

Side Effects of Vaprisol

  • There may be serious side effects if your blood sodium levels rise too quickly. Your healthcare professional will monitor your blood sodium levels and check for brain side effects.
  • Injection site reactions are the most common side effect of Vaprisol. Serious injection site reactions may require stopping Vaprisol.
  • Some other common side effects that may occur with Vaprisol include:
    • headache
    • thirst
    • low potassium
    • vomiting
    • increased urination
    • diarrhea
    • decrease in blood pressure upon standing that may cause faintness

Who Should Not Take Vaprisol

You should not be treated with Vaprisol if you:

  • Have too little sodium in the bloodstream and too little fluid in the body (hypovolemic hyponatremia)
  • are allergic to any of its ingredients
  • are taking medicines that can interact with Vaprisol, such as:
    • statin medicines, including:
      • simvastatin (Zocor, Vytorin)
      • lovastatin (Mevacor, Altocor, Advicor, Altoprev)
      • atorvastatin (Lipitor)
      • rosuvastatin (Crestor)
      • ketoconazole (Nizoral)
      • itraconazole (Sporanox)
      • clarithromycin (Biaxin)
      • ritonavir (Norvir, Kaletra)
      • indinavir (Crixivan)

Know the medicines you take. Keep a list of them with you to show your healthcare professional.

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