Zavesca

The below information on Zavesca has been taken from official FDA sources, but we cannot guarantee it's accuracy. Please use this site for educational purposes only. This site does not replace a proper discussion with your doctor.


    Brand Name:Zavesca
    Generic:Miglustat
    Availability:Prescription
This drug was approved by the FDA in one form or another on:
2003-07-31 ,
This drug is made in one form or another by the following companies:
Galen Limited; Actelion Pharmaceuticals US Inc.
This drug is available in the following forms:
Capsules
View the actual FDA approved label for this drug at the following links:
http://www.fda.gov/cder/foi/label/2003/21348_zavesca_lbl.pdf

About Zavesca

Zavesca is used to treat adults with mild to moderate type I Gaucher disease. Zavesca is only used in patients who cannot be treated with enzyme replacement therapy. Zavesca has not been studied in children under 18 years of age.

Type I Gaucher disease is an inherited disease that you get from both your parents. People with Type I Gaucher disease are missing an enzyme that breaks down a chemical in the body called glucosylceramide. Too much glucosylceramide causes liver and spleen enlargement, changes in the blood, and bone disease. Zavesca may stop glucosylceramide from forming.

Precautions for Zavesca

  • Zavesca can cause problems affecting your nerves (neurologic problems). It may cause hand tremors (shaky movements), or worsening of a hand tremor that you already have.
  • Zavesca may also cause numbness and tingling in your hands, arms, legs, or feet (peripheral neuropathy).

Side Effects of Zavesca

Diarrhea is the most common side effect for people taking Zavesca. You may also lose weight when you start treatment with Zavesca. Some of the other side effects of Zavesca include:

  • Gas
  • Stomach pain
  • Headache
  • Dizziness
  • Nausea
  • Constipation
  • Muscle cramps
  • Weakness
  • Cramps
  • Do not feel like eating
  • Vision problems
  • Low platelet count

Who Should Not Take Zavesca

Do not take Zavesca if you are allergic to any of its ingredients. The active ingredient is miglustat.

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