Zolinza

The below information on Zolinza has been taken from official FDA sources, but we cannot guarantee it's accuracy. Please use this site for educational purposes only. This site does not replace a proper discussion with your doctor.


    Brand Name:Zolinza
    Generic:Vorinostat
    Availability:Prescription
This drug was approved by the FDA in one form or another on:
2006-10-06 ,
This drug is made in one form or another by the following companies:
Merck & Co., Inc.
This drug is available in the following forms:
Capsules
View the actual FDA approved label for this drug at the following links:
http://www.fda.gov/cder/foi/label/2006/021991lbl.pdf

About Zolinza

Zolinza is a prescription medicine used to treat a type of cancer called cutaneous T-cell lymphoma (CTCL) in patients when the CTCL gets worse, does not go away, or comes back after treatment with other medicines.

Zolinza has not been studied in children under the age of 18.

Side Effects of Zolinza

The following are the major potential risks and side effects of Zolinza therapy. However, this list is not complete. Tell your healthcare professional right away if you have any of the following symptoms:

  • Blood clots in the legs (deep vein thrombosis)
  • sudden swelling in a leg
  • pain or tenderness in the leg. The pain may only be felt when standing or walking.
  • increased warmth in the area where the swelling is
  • skin redness or change in skin color
  • Blood clots that travel to the lungs (pulmonary embolus)
  • sudden sharp chest pain
  • rapid pulse
  • shortness of breath
  • fainting
  • cough with bloody secretions
  • feeling anxious
  • sweating
  • Dehydration(loss of too much fluid from the body). This can happen if you are having nausea, vomiting or diarrhea and can not drink fluids well.
  • Low blood cell counts:Your healthcare professional will periodically do blood tests to check your blood counts.
  • Low red blood cells.Low red blood cells may make you feel tired and get tired easily. You may look pale, and feel short of breath.
  • Low platelets.Low platelets can cause unusual bleeding or bruising under the skin. Talk to your healthcare professional right away if this happens.
  • High blood sugar(blood glucose). If you have high blood sugar or diabetes, monitor your blood sugar frequently as directed by your healthcare professional. Tell your healthcare professional right away if your blood sugar is higher than normal.
  • Electrocardiogram abnormality.An electrocardiogram, or EKG, is a test that records the electrical activity of your heart. Your healthcare professional will check your blood electrolytes and electrocardiogram periodically.
  • The most common side effects that may occur with Zolinza include: stomach and intestinal problems (including diarrhea, nausea, vomiting, loss of appetite, constipation and weight loss), tiredness, dizziness, headache, changes in the way things taste and dry mouth, muscle aches, hair loss, chills, fever, upper respiratory infection, cough, increase in blood creatinine, swelling in the foot, ankle and leg and itching.

Interactions with Zolinza

Especially tell your healthcare professional if you take:

  • Valproic acid: a medicine used to treat seizures. Your healthcare professional will decide if you should continue to take valproic acid and may want to test your blood more frequently.
  • Coumadin: (warfarin) or any other blood thinner. Ask your healthcare professional if you are not sure if you are taking a blood thinner. Your healthcare professional may want to test your blood more frequently.

Know the medicines you take. Keep a list of them with you to show your healthcare professional.

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