The below information on Zyprexa has been taken from official FDA sources, but we cannot guarantee it's accuracy. Please use this site for educational purposes only. This site does not replace a proper discussion with your doctor.

    Brand Name:Zyprexa
This drug was approved by the FDA in one form or another on:
1996-09-30 ,
This drug is made in one form or another by the following companies:
Eli Lilly and Company
This drug is available in the following forms:
View the actual FDA approved label for this drug at the following links:

About Zyprexa

  • Zyprexa is in a class of medications called atypical antipsychotics. Antipsychotic medicines are approved to treat symptoms of schizophrenia that may include hearing voices, seeing things, or sensing things that are not there, mistaken beliefs or unusual suspiciousness.
  • Zyprexa is approved to treat mixed or manic episodes in adults who have a condition called Bipolar I disorder.
  • Zyprexa may also be used with lithium or valproate for short-term treatment of acute manic episodes of bipolar disorder.

Precautions for Zyprexa

  • Dizziness, and sometimes fainting, caused by a drop in blood pressure may happen with Zyprexa, especially when you first start taking this medicine or when the dose is increased.
  • Zyprexa may impair judgment, thinking, or motor skills. You should be careful in operating machinery, including automobiles, until you know how Zyprexa affects you.
  • It is important to avoid overheating and dehydration while taking Zyprexa. Zyprexa may make it harder to lower your body temperature.

Side Effects of Zyprexa

The following are the risks and potential side effects ofZyprexa therapy. However, this list is not complete.

  • Increased chance of death in elderly persons. Elderly patients treated with atypical antipsychotics, such as Zyprexa, for dementia had a higher chance for death than patients who did not take the medicine. Zyprexa is not approved for dementia.
  • A life-threatening nervous system problem called neuroleptic malignant syndrome (NMS). NMS can cause a high fever, stiff muscles, sweating, a fast or irregular heart beat, change in blood pressure, and confusion. NMS can affect your kidneys. NMS is a medical emergency. Call your healthcare professional right away if you experience these symptoms.
  • A movement problem called tardive dyskinesia (TD). Call your healthcare professional right away if you get muscle movements that cannot be stopped.
  • High blood sugar and diabetes. Patients with diabetes or who have a higher chance for diabetes should have their blood sugar checked often.
  • Strokes have happened in older patients treated for mental illness from dementia. Zyprexa is not approved for this use.
  • Other serious side effects include low blood pressure seen as dizziness, and possibly fainting; increased heart beat; seizures; liver problems; increased body temperature; and difficulty swallowing.
  • The most common side effects include sleepiness, dry mouth, dizziness, restlessness, constipation, upset stomach, weight gain, increased appetite, and tremor.

Interactions with Zyprexa

Because certain other medications can interact with Zyprexa, review all medications that you are taking with your healthcare professional, including those that you take without a prescription.

Your healthcare professional may have to adjust your dose or watch you more closely if you take the following medications:

  • blood pressure medicines
  • levodopa and other medicines called dopamine agonists
  • omeprazole
  • rifampin
  • carbamazepine
  • fluvoxamine

Avoid drinking alcohol while taking Zyprexa.

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Recent Forum Posts on Zyprexa

For how long?

I have been on Zyprexa for more than 5 years. My doctor says that I cannot stop taking it unless I first replace it with another anti-psihotic. I tried Geodon and Abilify but it didn't work and now I am back on Zyprexa. I think it would be much easier to simply decrease the dose and then stop taking it. Has anyone tried to stop Zyprexa? Has any doctor approved/recommanded that?

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